SYN1 anticorps
Aperçu rapide pour SYN1 anticorps (ABIN5540676)
Antigène
Voir toutes SYN1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Specific for the ~78k synapsin I doublet in Western blots of rat brain extracts. Immunolabeling blocked by preadsorption of antibody with the protein used to generate the antibody.
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Purification
- Affinity purification using a column to which the native protein was coupled
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Immunogène
- Native protein purified from bovine brain
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Isotype
- Ig Fraction
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Indications d'application
- Western blot: 1/1000. Immunohistochemistry / immunoflourescence: 1:1000. Immunoprecipitation: 2 μL per 200 μg lysate.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg BSA per ml and 50 % glycerol
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Date de péremption
- 12 months
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- SYN1 (Synapsin I (SYN1))
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Autre désignation
- synapsin-1
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Sujet
- Synapsin I plays a key role in synaptic plasticity in brain (Feng et al., 2002 Nayak et al., 1996). This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. In addition to its role in plasticity, the expression of synapsin I is a precise indicator of synapse formation (Moore and Bernstein, 1989 Stone et al., 1994). Thus, synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation (Jovanovic et al., 2001 Kao et al., 2002).
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UniProt
- P17599
Antigène
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